What is the genetic cause of familial hemiplegic migraine (FHM) type 3?

Updated: Oct 21, 2019
  • Author: Jasvinder Chawla, MD, MBA; Chief Editor: Helmi L Lutsep, MD  more...
  • Print
Answer

FHM type 3 is caused by mutations in the SCN1A gene, located on 2q24. Mutations in SCN1A are also known to cause familial febrile seizure disorders and infantile epileptic encephalopathy. [38] Although SCN1A mutation has been reported in several unrelated families, it is felt to be a rare cause of FHM. [39]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!