Which medications in the drug class Calcium Channel Blockers are used in the treatment of Cluster Headache?

Updated: Jun 07, 2019
  • Author: Michelle Blanda, MD; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Answer

Calcium Channel Blockers

These agents inhibit the initial vasoconstrictive phase of CH.

Verapamil (Calan, Verelan, Verelan PM, Covera-SR)

Perhaps the most effective calcium channel blocker for CH prophylaxis, verapamil inhibits calcium ions from entering slow channels, select voltage-sensitive areas, or vascular smooth muscle, thereby producing vasodilation. It can be combined with ergotamine or lithium.


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