Which medications in the drug class Anticonvulsants, Other are used in the treatment of Chronic Paroxysmal Hemicrania?

Updated: Jun 12, 2019
  • Author: Monica Saini, MD, MBBS; more...
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Anticonvulsants, Other

Agents with state-dependent sodium channel–blocking action and inhibitory activity of the neurotransmitter GABA may have prophylactic effects on CPH.

Topiramate (Topamax)

Topiramate is a sulfamate-substituted monosaccharide with a broad spectrum of antiepileptic activity that may have state-dependent sodium channel–blocking action. This agent potentiates the inhibitory activity of the neurotransmitter GABA and may block glutamate activity. It is not necessary to monitor plasma concentrations to optimize therapy.

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