What is the role of nerve conduction studies in the diagnosis of peroneal mononeuropathy?

Updated: Jun 08, 2018
  • Author: Shaheen E Lakhan, MD, PhD, MS, MEd; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Nerve conduction studies and needle EMG aid in defining the location and type of lesion.

  • Nerve conductions should show isolated peroneal nerve abnormalities. If the lesion is at the knee, then conduction block or, less commonly, conduction velocity slowing over that segment of the nerve should be documented. When axonal loss occurs in direct nerve trauma or with long-standing compression, a small compound muscle action potential may be noted. If other mononeuropathies with conduction blocks are found, then consideration should be made for an underlying vasculitis causing mononeuritis multiplex or possibly for hereditary neuropathy with liability to pressure palsy. If more diffuse nerve abnormalities are noted, then a generalized neuropathy should be considered, especially chronic inflammatory demyelinating polyneuropathy.

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