What is the role of somatosensory evoked potentials (SEPs) in the evaluation of brain stem lesions and stroke?

Updated: Aug 20, 2019
  • Author: Jasvinder Chawla, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
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SEPs are normal in Wallenberg's syndrome but are generally abnormal when medial lemniscus is involved. SEPs are also unaffected and normal in some of the hemispheric (eg, pure motor lacunar infarctions, occipital lobe infarctions). In larger brainstem or hemispheric lesions, N20 and later waveforms may be delayed or absent. In lesions of the thalamocortical radiations, dissociation between the N20 and P22 waveform amplitudes may be observed. Changes in SEPs over time have been explored for their predictive value for recovery from stroke. This area remains investigational.

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