What is the risk of motor evoked potentials (MEPs)-related seizures?

Updated: Aug 20, 2019
  • Author: Jasvinder Chawla, MD, MBA; Chief Editor: Selim R Benbadis, MD  more...
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Seizures are reported rarely in seizure-prone individuals. Stimulation at a high rate clearly can induce seizures, even in healthy subjects, but the effect of low-rate stimulation is controversial. Some studies suggest a beneficial role for TMS in decreasing the frequency of epileptic seizures. Patients with epilepsy still are excluded routinely from magnetic stimulation studies.

Kindling (ie, induction of permanent seizure focus) has never been induced in animals with stimulation at less than 10Hz, despite prolonged stimulation.

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