What EEG findings are characteristic of lithium encephalopathy?

Updated: Oct 09, 2019
  • Author: Eli S Neiman, DO, FACN; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Lithium

Encephalopathy, confusional states, and nonconvulsive status epilepticus due to lithium toxicity and overdose is well documented. [73] In a report by Bellesi et al, a patient presented in nonconvulsive status epilepticus with a normal serum lithium level that resolved with benzodiazepine administration and withdrawal of the lithium. After 2 months , the lithium was restarted with therapeutic levels attained. The patient again was found to be in NCSE with 3-4 Hz diffuse spike and wave discharges. The lithium was stopped, never to be readministered. [74]


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