What EEG findings are characteristic of mitochondrial encephalomyopathy?

Updated: Oct 09, 2019
  • Author: Eli S Neiman, DO, FACN; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Isozumi et al described a 50-year-old woman with subacute dementia and myoclonus in whom computed tomography (CT) revealed brain atrophy and EEG revealed periodic synchronous discharges (PSDs). She initially was thought to be suffering from Creutzfeldt-Jakob disease (CJD) but dramatically recovered over 5 months. On the basis of further investigations, the final diagnosis was mitochondrial encephalomyopathy. In general, the EEG changes were described as background slowing, multifocal epileptiform discharges, and photosensitivity.


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