What EEG findings are characteristic of corticobasal degeneration (CBD)?

Updated: Oct 09, 2019
  • Author: Eli S Neiman, DO, FACN; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Answer

Corticobasal degeneration (CBD) is a neurodegenerative disorder and tauopathy characterized by progressive dementia and asymmetrical rigidity and limb apraxia. Tashiro et al found prominent focal slowing on EEG in the anterior and temporal head regions in early CBD in 8 of 10 patients studied. [27] Frontal intermittent rhythmic delta activity was also observed but was not found to be specific to CBD.

Roche et al evaluated 5 patients with CBD, of whom none had REM behavioral disorder (as is often seen in many neurodegenerative disorders) or excessive daytime sleepiness. All 5 patients with CBD had insomnia, 4 had periodic limb movements or restless legs syndrome, and 2 had sleep respiratory disorders. [28]


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