What EEG findings are characteristic of dementia with Lewy bodies (DLB)?

Updated: Oct 09, 2019
  • Author: Eli S Neiman, DO, FACN; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Answer

In a study comparing patients with dementia with Lewy bodies (DLB) and patients with AD, Briel et al found that 17 of the total 19 records from the patients with DLB) were abnormal. [20] Thirteen showed loss of alpha activity as the dominant rhythm, and half had slow wave transient activity in the temporal lobe areas. This slow wave transient activity correlated with a clinical history of loss of consciousness. The patients with AD were less likely to show transient slow waves and tended to have less marked slowing of dominant rhythm.

The greater slowing of the EEG in DLB than in AD may be related to a greater loss of choline acetyltransferase found in DLB. Temporal slow wave transients may be a useful diagnostic feature in DLB and may help to explain the transient disturbance of consciousness, which is characteristic of DLB. [21, 22]


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