What is Lennox-Gastaut syndrome (LGS)?

Updated: Oct 01, 2020
  • Author: Raj D Sheth, MD; Chief Editor: Selim R Benbadis, MD  more...
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Lennox-Gastaut syndrome (LGS) is a childhood (onset, age 3–5 y) epileptic encephalopathy that manifests with atonic seizures, tonic seizures, and atypical absence seizures associated with mental retardation and a characteristic electroencephalographic (EEG) pattern. Infantile spasms and West syndrome frequently transform into Lennox-Gastaut syndrome. However, unlike West syndrome, Lennox-Gastaut syndrome tends to be a lifelong epileptic encephalopathy.

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