Which medications in the drug class Osmotic Diuretics are used in the treatment of Subdural Hematoma?

Updated: Jul 26, 2018
  • Author: Richard J Meagher, MD; Chief Editor: Helmi L Lutsep, MD  more...
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Osmotic Diuretics

These agents may help reduce intracranial pressure.

Mannitol (Osmitrol)

Mannitol may reduce subarachnoid space pressure by creating an osmotic gradient between the cerebrospinal fluid in the arachnoid space and the plasma. It is not for long-term use. Initially assess for adequate renal function in adults by administering a test dose of 200 mg/kg, given IV over 3-5 min; this should produce urine flow of at least 30-50 mL/h of urine over 2-3 hours.

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