What is the role of selegiline in the treatment of Alzheimer disease (AD) in Down syndrome (DS)?

Updated: Nov 13, 2019
  • Author: Norberto Alvarez, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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Answer

Answer

Selegiline is a neuro protective medication that might be of benefit in persons with DS. [143] A Cochrane meta-analysis of selegiline failed to show any positive effect. This medication has not been evaluated in persons with DS. [144]

In many instances, medications might be needed to treat the frequent comorbid conditions observed in persons with DS. [145]


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