Which clinical history findings are characteristic of middle stage Alzheimer disease (AD) in Down syndrome (DS)?

Updated: Nov 13, 2019
  • Author: Norberto Alvarez, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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In the middle stage, the ability to perform ADLs markedly deteriorates. The patient may depend totally on others for activities such as dressing, eating, walking, and toilet needs. Communication skills are also reduced markedly; speech and language, if present, are not used efficiently. Behavioral problems are exaggerated, psychotic behavior may be displayed, and social activities are reduced to a minimum.

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