What is the link between Alzheimer's disease and frontotemporal dementia (FTD)?

Updated: Jun 14, 2018
  • Author: Howard S Kirshner, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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Answer

Answer

Alzheimer disease, by far the most common dementing pathology, has also been associated with syndromes of PPA and FTD in some cases. [5, 39, 40, 41] Alzheimer disease is uncommonly found at autopsy in patients with primary progressive, nonfluent aphasia, but the association is more common in semantic dementia and is especially frequent in patients with logopenic progressive aphasia. The relationship of Alzheimer disease to the primary progressive aphasia syndromes is covered in more detail in the section on Primary Progressive Aphasia. In addition, there is now a recognized syndrome of “frontal variant Alzheimer disease”.


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