What are the CSF findings in dementia with Lewy bodies (DLB)?

Updated: Aug 08, 2019
  • Author: Howard A Crystal, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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Answer

Cerebrospinal fluid (CSF) examination is not required in routine cases. However, CSF findings in DLB include the following:

  • Patients with Alzheimer disease have higher levels of tau protein in their CSF than do patients with DLB

  • Patients with LB variant of Alzheimer disease (LBV-AD) have intermediate values

  • CSF levels of beta amyloid are lower than normal in DLB, Alzheimer disease, and LBV-AD; however, CSF beta-amyloid levels in DLB, LBV-AD, and Alzheimer disease do not differ from each other [13]


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