What are the cognitive function findings in dementia with Lewy bodies (DLB)?

Updated: Aug 08, 2019
  • Author: Howard A Crystal, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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Answer

Patients with DLB usually have impaired cognition consistent with dementia. Cognitive function, as measured by Mini-Mental State Examination (MMSE) scores, appears to be relatively preserved in DLB compared with Alzheimer disease (AD) or AD+DLB (P< .01). Nelson et al evaluated data from 2 large, multicenter data registries (6,340 cases in total) and found that final MMSE scores were 15.6 (+/- 8.7) in persons with DLB, 10.7 (+/- 8.6) in persons with Alzheimer disease, and 10.6 (+/- 8.6) in those with AD+DLB. [12]


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