Which physical findings are characteristic of dermatologic disorders due to chronic hepatitis C (CHC) infection?

Updated: Apr 19, 2019
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Answer

Cryoglobulinemia with leukocytoclastic and necrotizing small vessel vasculitis of the skin, kidneys, joints, and eyes. Physical findings in the skin include palpable purpura and ulcerations on the lower legs.

Sialadenitis presents as dry eyes and dry oral and nasal mucosa. Ulcerations occur late in the evolution of this disorder.

In Mooren corneal ulcer, corneal ulcers form on one or both eyes beginning at the periphery or limbus.

Antiphospholipid syndrome results in protean physical findings in the brain, kidneys, eyes, skin, joints, and major vessels because of thrombus formation and bleeding in these major organs.


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