What is the prevalence of porphyria cutanea tarda (PCT) in chronic hepatitis C (CHC)?

Updated: Mar 26, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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In southern Europe where HCV is prevalent, 70-90% of patients with PCT have positive results for HCV. Patients with familial PCT had negative results for HCV in one study. All patients with PCT with HCV had active multiplication of HCV.

In northern Europe, Australia, and England where the prevalence of HCV is lower, 20% of patients with PCT have detectable levels of HCV. In these countries, PCT is more closely related to the higher prevalence of the hemochromatosis gene abnormality.

In the United States, the prevalence of HCV in patients with PCT is intermediate at 56%.

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