What is the prevalence of pruritus in hepatitis C (Hep C)?

Updated: Mar 26, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Extrahepatic manifestations of HCV infection occur in 74% of patients. [43] Pruritus is one of the most common symptoms, occurring in 15% of patients. A study of HCV infection with pruritus showed that nonspecific lesions were associated with pruritus in two thirds of patients. Urticaria occurred in 5 of 29 patients, with urticarial vasculitis occurring in 1 patient. Atopic dermatitis occurred in 2 of 29 patients with HCV infection. LP was present in 4 of 29 patients, and cryoglobulinemia was present in 10 of 29 patients. Most patients in this group had xerosis and keratosis pilaris that were easily alleviated with emollients. Prurigo nodularis is more common in patients with HCV and pruritus than in other patients.

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