What is the pathogenesis of Mooren corneal ulcer in chronic hepatitis C (CHC)?

Updated: Apr 02, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Answer

Necrolytic acral erythema, a rare disorder, has been linked with HCV infection. [22]

Cross-reactivity to HCV envelope protein and a corneal antigen appears to be causative. A HCV envelope protein shares the antigenic specificity of this protein, resulting in Mooren ulcer in HCV infection. Other common etiologic causes may occur.


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