What are the most common extrahepatic manifestation of hepatitis C (Hep C)?

Updated: Mar 26, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Extrahepatic manifestations of HCV are numerous. [1] The most prevalent and most closely linked with HCV is essential mixed cryoglobulins with dermatologic, neurologic, renal, and rheumatologic complications. It is evident in up to half of patients with chronic hepatitis C infection. [2, 3] A less definite relationship to HCV is observed with systemic vasculitis, porphyria cutanea tarda, and the sicca syndromes. [4, 5, 6, 7]

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