Which medications in the drug class Antineoplastics, Antibiotic are used in the treatment of Nongenital Warts?

Updated: Sep 25, 2020
  • Author: Philip D Shenefelt, MD, MS; Chief Editor: William D James, MD  more...
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Antineoplastics, Antibiotic

Antibiotic antineoplastics inhibit cell growth and proliferation.


Bleomycin is a cytotoxic polypeptide that inhibits DNA synthesis in cells and viruses. It has affinity for HPV-infected tissue and induces vascular changes that result in epidermal necrosis. Bleomycin has been beneficial in treating resistant warts. Reserve this as a third-line treatment when standard therapies have failed. Inject 0.5-1 U/mL solution directly into the wart, not to exceed 1.5 U/treatment; less painful administration involves placing 1 mg/mL gtt onto wart and pricking it into the wart with a needle.

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