Which medications in the drug class Histamine H2 receptor antagonists are used in the treatment of Nongenital Warts?

Updated: Sep 25, 2020
  • Author: Philip D Shenefelt, MD, MS; Chief Editor: William D James, MD  more...
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Histamine H2 receptor antagonists

These type 2 histamine receptor antagonists are commonly used to treat peptic ulcer disease; owing to their immunomodulatory effects at higher doses, they have been used as treatment for warts. Results have been variable, and double-blinded, placebo-controlled studies have shown no benefit.

Cimetidine (Tagamet)

Cimetidine is believed to have immunomodulatory effects at higher doses. It may be administered at 20-40 mg/kg PO qd divided q6h, not to exceed 2400 mg/day.

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