What are histologic features of deep palmoplantar nongenital warts (myrmecia)?

Updated: Sep 25, 2020
  • Author: Philip D Shenefelt, MD, MS; Chief Editor: William D James, MD  more...
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Deep palmoplantar warts appear similar to common warts except that most of the lesion lies deep to the plane of the skin surface. This endophytic epidermal growth often has the distinctive feature of polygonal, refractile-appearing, eosinophilic, cytoplasmic inclusions composed of keratin filaments, forming ringlike structures. Basophilic nuclear inclusions and basophilic parakeratotic cells loaded with virions may be in the upper layers of the epidermis.

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