What is the medical care of roseola infantum?

Updated: Oct 09, 2020
  • Author: Christopher R Gorman, MD; Chief Editor: William D James, MD  more...
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At present, no medical antiviral therapy is available for human herpesvirus 6 (HHV-6) infection that causes roseola. Thus, treatment of roseola infantum is supportive. [13] However, in 2002, Rapaport et al reported that antiviral prophylaxis with ganciclovir may prevent HHV-6 reactivation in high-risk bone marrow transplant patients. [14] Further double-blinded randomized studies are needed.

Short- or long-term antiseizure medications are not recommended for infants who have had a febrile seizure secondary to roseola.

Inpatient care for roseola infantum consists of support with antipyretics and treatment of gastroenterologic, respiratory, hematologic, or CNS complications.

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