Which medications in the drug class Vaccines, Live, Viral are used in the treatment of Herpes Zoster?

Updated: Feb 11, 2021
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Vaccines, Live, Viral

Vaccines consist of attenuated microorganisms or cellular components, which act as antigens. VZV vaccines elicit active immunization to increase resistance to infection. Administration stimulates antibody production with specific protective properties.

Varicella-zoster vaccine (Zostavax)

Zostavax is a lyophilized preparation of the Oka/Merck strain of live, attenuated VZV. It has been shown to boost immunity against herpes zoster virus (shingles) in older patients. It has been shown to reduce the occurrence of shingles by about 50% in individuals older than 60 years, by 64% in those aged 60-69 years, and by 70% in subjects aged 50-59 years. It also slightly reduces pain compared with no vaccination in those who develop shingles. The vaccine is indicated for the prevention of herpes zoster in patients who have no contraindications.

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