Which medications in the drug class Analgesics are used in the treatment of Herpes Zoster?

Updated: Feb 11, 2021
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
  • Print


Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and facilitate physical therapy. Most oral narcotic analgesics have sedating properties that are beneficial for patients who have skin lesions.

Oxycodone (OxyContin, Roxicodone, Oxecta)

Oxycodone is a narcotic analgesic that is indicated for the relief of moderate to severe pain. Patients with herpes zoster usually experience pain. Antiviral and steroid therapies provide relatively minor relief of pain, and narcotic analgesics are often needed.

Acetaminophen (Tylenol, APAP 500, FeverAll)

Acetaminophen is indicated for use in patients with mild pain or fever. It is the drug of choice for the treatment of pain in patients who (1) have documented hypersensitivity to aspirin or NSAIDs, (2) have upper gastrointestinal (GI) disease, or (3) are taking oral anticoagulants. Acetaminophen reduces fever via direct action on hypothalamic heat-regulating centers, which increases dissipation of body heat via vasodilation and sweating.

Ibuprofen (Advil, Motrin, Caldolor)

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is the drug of choice for treatment of mild to moderately severe pain, if no contraindications exist. It inhibits inflammatory reactions and pain, probably by decreasing the activity of the enzyme cyclooxygenase and thereby, in turn, inhibiting prostaglandin synthesis. Ibuprofen is one of the few NSAIDs that are indicated for fever reduction.

Naproxen (Aleve, Naprosyn, Naprelan, Anaprox)

Naproxen another NSAID that is commonly used for the relief of mild to moderate pain. It inhibits inflammatory reactions and pain by decreasing the activity of cyclooxygenase, an effect that results in a decrease of prostaglandin synthesis.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!