What is the role of IV acyclovir in the treatment of herpes zoster (shingles)?

Updated: Feb 11, 2021
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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IV acyclovir remains the drug of choice for the following populations of immunocompromised patients:

  • Patients with evidence of disseminated disease or visceral organ involvement

  • Patients with ophthalmic involvement

  • Patients with advanced HIV/AIDS who harbor active opportunistic infections or exhibit prominent wasting

  • Transplant recipients who have just undergone transplantation or are being treated for rejection

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