Which is the role of PCR assay testing in the diagnosis of herpes zoster (shingles)?

Updated: Jan 25, 2019
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

PCR assay of vesicular fluid or a corneal scraping can yield the VZV nucleic acid. Detection of VZV DNA in plasma can facilitate the early recognition of VZV infection in immunocompromised hosts. [78] [#WorkupSkinBiopsyFindings]In cases of zoster sine herpete, DNA analysis by means of PCR appears more useful than the standard assays, especially for early diagnosis.


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