What is suggested by a finding of herpes zoster involving multiple dermatomes?

Updated: Feb 11, 2021
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Involvement of more than 1 dermatomal distribution in unilateral zoster is rare and usually is considered a harbinger of significant compromise of the immune system caused by AIDS, malignancy, chemotherapy, and other factors. Involvement of 2 dermatomes may be referred to as zoster duplex, and involvement of 3 or more may be referred to as zoster multiplex.

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