What are the treatment options for postherpetic neuralgia (PHN) of herpes zoster (shingles)?

Updated: Feb 11, 2021
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Prompt treatment of acute zoster and its associated pain (eg, with antiviral therapy) can prevent the development of PHN. Once PHN has developed, various treatments are available, including the following:

  • Neuroactive agents (eg, TCAs) [6]

  • Anticonvulsant agents (eg, gabapentin, [7] pregabalin)

  • Narcotic and nonnarcotic analgesics, both systemic (eg, opioids) and topical

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