How is HSV erythema multiforme treated?

Updated: Feb 16, 2018
  • Author: Sean P McGregor, DO, PharmD; Chief Editor: William D James, MD  more...
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Answer

HSV is the most common cause of erythema multiforme, and recurrences of erythema multiforme parallel recurrences of herpes simplex. Long-term suppressive therapy can be used for patients with six or more episodes per year or for those with severe recurrences. Long-term suppressive therapy with acyclovir has been shown to suppress recurrences of erythema multiforme in approximately 60% of patients. [53] Dosing of systemic antivirals for recurrent herpes labialis or genitalis can be used, as the majority of evidence is derived from small studies and case reports.


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