What are the nondermatologic indications for extracorporeal photopheresis (ECP)?

Updated: Nov 21, 2016
  • Author: Vikas Shrivastava, MD; Chief Editor: William D James, MD  Dirk M Elston, MD  more...
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Evidence indicates that extracorporeal photopheresis (ECP) is effective for the treatment of persistent acute lung transplant rejection and refractory chronic lung transplant rejection. [1] Likewise, studies have indicated the value of adjunctive ECP in the treatment of heart transplant rejection. [1]

Evidence also exists for the benefit of ECP in the following [1, 9, 25] :

  • Kidney transplant rejection

  • Liver transplant rejection

  • Face transplantation

  • Prophylaxis against heart transplant rejection

  • Crohn disease

  • Type 1 diabetes mellitus

  • Multiple sclerosis

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