What are the possible adverse effects of extracorporeal photopheresis (ECP)?

Updated: Nov 21, 2016
  • Author: Vikas Shrivastava, MD; Chief Editor: William D James, MD  Dirk M Elston, MD  more...
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Extracorporeal photopheresis (ECP)is a safe, well-tolerated procedure. However, known adverse effects include the following [1, 7] :

  • Transient hypotension

  • Tachycardia

  • Low-grade anemia

  • Thrombocytopenia

Absolute and relative contraindications to ECP include the following [1] :

  • Sensitivity to psoralen compounds

  • Pregnancy

  • History of heparin-induced thrombocytopenia

  • Unsatisfactory cardiac function

  • Anemia

  • Photosensitive comorbidities

  • Aphakia

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