What is the dermatologic preoperative evaluation and management of antibiotic allergies?

Updated: Mar 16, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Surgeons frequently use both systemic antibiotics and topical antibiotics, necessitating inquiry into possible adverse reactions. Topical antibiotics can cause sensitization, especially when used for a prolonged period. White petrolatum is a safe and less costly alternative to bacitracin for healing uncontaminated cutaneous wounds with less risk of allergy and secondary colonization. Evaluation of new tinted 2% chlorhexidine gluconate/70% isopropyl alcohol film-forming sterile preoperative skin preparation showed it does not interfere with antimicrobial efficacy and it does not demonstrate a potential for the development of resistance or cross-resistance with antibiotics. [7]

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