Which medications in the drug class Immunosuppressants are used in the treatment of Wells Syndrome?

Updated: Apr 17, 2019
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Answer

Immunosuppressants

Immunosuppressant agents inhibit key factors in the immune system responsible for immune reactions.

Cyclosporine (Sandimmune, Neoral, Gengraf)

Cyclosporine has been demonstrated to be helpful in a variety of skin disorders.

Cortisone

Cortisone decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability.

Prednisone

Prednisone may decrease inflammation by reversing increased capillary permeability and suppressing polymorphonuclear activity.

Hydrocortisone topical (Cortaid Advanced, Dermacort, Westcort, Ala-Cort, HydroSKIN)

Hydrocortisone is an adrenocorticosteroid derivative suitable for application to skin or external mucous membranes. It decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability.

Dexamethasone (Baycadron)

Dexamethasone is used for various allergic and inflammatory diseases. It decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reducing capillary permeability.

Betamethasone (Diprolene, Celestone, Celestone Soluspan, Luxiq)

Betamethasone is used for inflammatory dermatoses responsive to steroids. It decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing capillary permeability. It affects production of lymphokines and has an inhibitory effect on Langerhans cells.


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