Which medications in the drug class Corticosteroids are used in the treatment of Vesicular Palmoplantar Eczema?

Updated: Aug 23, 2019
  • Author: Jessica Dunkley, MD, MHSc, CCFP; Chief Editor: Dirk M Elston, MD  more...
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These agents have anti-inflammatory properties and cause profound and varied metabolic effects. They modify the immune response of the body to diverse stimuli.

Betamethasone dipropionate topical (Diprolene)

Betamethasone dipropionate topical is for inflammatory dermatoses responsive to steroids. It decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability. It affects the production of lymphokines and has inhibitory effect on Langerhans cells.

Clobetasol (Temovate, Olux-E, Temovate E, Cormax)

Clobetasol is a class I superpotent topical steroid; it suppresses mitosis and increases the synthesis of proteins that decrease inflammation and cause vasoconstriction.

Halobetasol (Ultravate)

Halobetasol is a class 1, superpotent topical steroid. It has antiinflammatory, antipruritic, and vasoconstrictive activity.


Prednisone is an immunosuppressant used to treat autoimmune disorders; it may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity. It stabilizes lysosomal membranes and suppresses lymphocytes and antibody production.

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