Which dermatologic conditions should be included in the differential diagnoses of sarcoidosis?

Updated: Oct 01, 2020
  • Author: Joseph F Merola, MD, MMSc; Chief Editor: Dirk M Elston, MD  more...
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Dermatologic conditions to consider in the differential diagnosis of sarcoidosis include the following:

  • Cutaneous tuberculosis

  • Drug eruptions

  • Granuloma annulare

  • Granuloma faciale

  • Lamellar ichthyosis

  • Leprosy

  • Lichen planus

  • Discoid lupus erythematosus

  • Subacute cutaneous lupus erythematosus

  • Lymphocytoma cutis

  • Necrobiosis lipoidica

  • Plaque psoriasis

  • Syphilis

  • Tinea corporis

B-cell lymphoma, foreign body reaction (including hypersensitivity granulomatous reaction to tattoo pigment), and lichen planopilaris should also be considered in the differential diagnosis. Silica granulomas are often associated with sarcoidosis, and patients on targeted immunotherapy for melanoma may develop sarcoidal granulomas. [14, 15, 16, 17]

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