How is cutaneous involvement in sarcoidosis classified?

Updated: Jul 30, 2018
  • Author: Joseph F Merola, MD, MMSc; Chief Editor: Dirk M Elston, MD  more...
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Answer

Answer

Cutaneous involvement is classified as either "specific" or "nonspecific". Histopathologically, specific lesions manifest as noncaseating granulomas, whereas nonspecific lesions do not reveal granulomas on histopathologic examination. Erythema nodosum (EN) (shown below) is the main nonspecific cutaneous disease. Lupus pernio, maculopapular, nodular, scar, plaque, angiolupoid, ichthyosiform, lichenoid, annular, verrucous, psoriasiform, and ulcerative lesions and subcutaneous nodules are examples of specific cutaneous disease.

Erythema nodosum. Erythema nodosum.

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