Which medications in the drug class Corticosteroids are used in the treatment of Nummular Dermatitis (Nummular Eczema)?

Updated: Nov 21, 2019
  • Author: Jami L Miller, MD; Chief Editor: William D James, MD  more...
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Corticosteroids have anti-inflammatory properties and cause profound and varied metabolic effects. In addition, they modify the body's immune response to diverse stimuli.

Triamcinolone topical (Aristocort) Cream or Ointment

Triamcinolone topical is used for inflammatory dermatosis responsive to steroids; it decreases inflammation by suppressing migration of PMN leukocytes and reversing capillary permeability. It is a good choice once lesions stabilize and the threat of secondary infection has passed. Use 0.025-0.1% strength.

Prednisone (Deltasone, Meticorten, Orasone)

Prednisone is for severe generalized flares. It may decrease inflammation by reversing increased capillary permeability and suppressing PMN leukocyte activity.

Clobetasol (Clarelux, Clobex, Clobex Spray)

Clobetasol propionate is a class I superpotent topical steroid; it suppresses mitosis and increases synthesis of proteins that decrease inflammation and cause vasoconstriction. Clobetasol propionate decreases inflammation by stabilizing lysosomal membranes, inhibiting PMN and mast cell degranulation.

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