What are the treatment options for localized granuloma annulare?

Updated: Oct 29, 2018
  • Author: Ruby Ghadially, MBChB, FRCP(C)Derm; Chief Editor: William D James, MD  more...
  • Print
Answer

Localized granuloma annulare (GA) is not often symptomatic and it has a tendency towards spontaneous resolution. Reassurance is often all that is necessary. Painful or disfiguring lesions have been treated by various methods, although the level of evidence supporting these methods is low.

Localized lesions have been treated with potent topical corticosteroids with or without occlusion for 4-6 weeks, as well as with intralesional corticosteroids with varying total doses of steroid.

Cryotherapy using liquid nitrogen or nitrous oxide as refrigerants has been shown in a prospective, uncontrolled trial to be an effective treatment for localized granuloma annulare. Secondary dyschromia may be a complication of cryotherapy. [12]

Laser therapy, using multiple different modalities including pulsed dye and excimer, has been successfully used for both localized and generalized granuloma annulare. [13, 14, 15, 16, 17]

Other anecdotes of therapeutic efficacy in both localized and generalized granuloma annulare involve tacrolimus and pimecrolimus [18, 19, 20, 21, 22, 23] and imiquimod cream. [24, 25]


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!