What is the role of ultraviolet A (UVA) light in the treatment for dyshidrotic eczema (dyshidrosis) (pompholyx)?

Updated: Apr 22, 2020
  • Author: Sadegh Amini, MD; Chief Editor: William D James, MD  more...
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Paradoxically, although sometimes linked as a possible cause, UVA or UVA-1 alone or with oral or topical psoralen has been used in treatment. Hand and/or foot UVA therapy (UVA or UVA-1 alone or with oral or topical psoralen) improves the eruption and pruritus when administered 2-3 times per week. The dose typically starts at 0.5 J per treatment and is increased by 0.5 J at every other or every third treatment. [38, 39]

Topical application of 8-methoxypsoralen plus UVA (bath-PUVA) has been demonstrated to be the preferred method for the treatment of dyshidrotic eczema, compared with oral PUVA. [40] Local, narrow-band UVB has been shown to be as effective as bath-PUVA in patients with chronic hand eczema of dry and dyshidrotic types. [41]

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