What causes polymorphous light eruption (PMLE)?

Updated: Jan 22, 2020
  • Author: Saud A Alobaida, MBBS, FRCPC; Chief Editor: Dirk M Elston, MD  more...
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Answer

The UVA light spectrum is the most common causative factor in polymorphous light eruption (PMLE). Other wavelengths, including UVB or even visible light, may also induce PMLE in some individuals. PMLE-like lesions have been reported in welders, resulting from exposure to UVC light. [23]

Overall, family history is positive for PMLE in about 15-20% of the patients. However, Native Americans have a hereditary form of PMLE with apparent autosomal dominant inheritance; 75% reveal disease in a family member. [24]


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