What is the role of ultrasonography in the workup of Chédiak-Higashi syndrome (CHS)?

Updated: Aug 08, 2019
  • Author: Roman J Nowicki, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Ultrastructural observations of periodontal polymorphonuclear leukocytes reveal defective granulation, with abnormal granules not discharging their lysosomal content against the engulfed bacteria. Viable dividing bacteria are found in the cytoplasm.


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