What is the role of skin biopsy in the diagnosis of lichen striatus?

Updated: Mar 26, 2020
  • Author: June Kim, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Skin biopsy can be performed to confirm the diagnosis of lichen striatus, but this is rarely necessary.

In ambiguous cases, direct immunofluorescence with staining for Civatte bodies has been proposed to distinguish between lichen planus and lichen striatus. Stains for immunoglobulin M, immunoglobulin G, and complement C3 are positive in lichen planus and negative in lichen striatus.


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