Which medications in the drug class Corticosteroids are used in the treatment of Granuloma Gluteale Infantum?

Updated: May 27, 2021
  • Author: Marlene T Dytoc, MD, PhD, FRCPC; Chief Editor: Dirk M Elston, MD  more...
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Answer

Corticosteroids

Intralesional administration is indicated to treat localized hypertrophic, infiltrated inflammatory lesions. Granuloma gluteale infantum, granuloma gluteale adultorum, and diaper area granuloma of the aged fit into this category of lesions. Flurandrenolide-impregnated tape, which combines a barrier with an anti-inflammatory action, has been reported to be beneficial.

Triamcinolone (Kenalog-10)

Triamcinolone is for inflammatory dermatosis responsive to steroids; it decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability. Intramuscular injections may be used for widespread skin disorders or intralesional injections may be used for localized skin disorders.

Each mL of sterile, aqueous suspension contains triamcinolone acetonide 10 mg. Nonmedicinal ingredients include benzyl alcohol, carboxymethylcellulose sodium, hydrochloric acid, polysorbate, sodium chloride, sodium hydroxide, and water. It is suspended in sterile sodium chloride solution at a final concentration of 2.5-5 mg/mL.

Flurandrenolide (Cordran tape)

Flurandrenolide is a topical anti-inflammatory agent supplied as a 4 mcg/cm2 topical adhesive tape. Despite the possible causative role of topical corticosteroids in some cases of granuloma gluteale infantum, various hypertrophic lesions have been effectively thinned in 3 days with the use of this treatment.


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