What is the medical care for Gianotti-Crosti syndrome?

Updated: Aug 13, 2019
  • Author: Kara N Shah, MD, PhD; Chief Editor: William D James, MD  more...
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Education and reassurance are usually sufficient for concerned parents. Some children may require general supportive and symptomatic care for the associated viral or streptococcal infection.

Application of soothing, anti-itch topical preparations with menthol, colloidal oatmeal, or pramoxine in conjunction with oral antihistamines may be useful for relief of pruritus. Use of topical corticosteroids or calcineurin inhibitors may be considered but are of questionable efficacy. If an associated streptoccocal or other bacterial infection is identified, a course of an appropriate systemic antibiotic should be initiated.

One report describes rapid resolution of a case of Gianotti-Crosti syndrome occurring in a 6-year-old girl after administration of oral ribavirin. [41]

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