What is the treatment of choice for scabies?

Updated: Oct 13, 2020
  • Author: Megan Barry, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

The mainstay of scabies treatment is the application of topical scabicidal agents, with repeat application in 7 days. The treatment of choice is permethrin 5% lotion. A 2007 Cochrane Review found that topical permethrin appeared to be the most effective treatment for scabies. [69]  Alternative drug therapy includes precipitated sulfur 6% in petrolatum, lindane, benzyl benzoate, crotamiton, and ivermectin; a possible new option is albendazole. [70, 71, 72, 73]  Regarding ivermectin,  a second course of treatment is often recommended 7-10 days later because of some developing larvae that may survive the initial treatment. [74]


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