What is the drug of choice for the treatment of scabies?

Updated: Oct 13, 2020
  • Author: Megan Barry, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

A scabicidal agent, such as permethrin, lindane, or ivermectin, is administered to destroy S scabiei mites, with an appropriate antimicrobial agent used as well if a secondary infection has developed. Moxidectin and afoxolaner are emerging as promising new agents. Botanical oils have also been used, but they present a risk of allergic contact dermatitis. Despite the development of resistance, permethrin retains good efficacy. [59, 60, 61, 62]


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